Botox® is the trade-name for a preparation of botulinum toxin, a chemical synthesized by the Clostridium botulinum bacterium. It causes paralysis of muscles by blocking the nerve signal that stimulates contraction of the muscle.

Botox® injections are most effective when used to treat those wrinkles that are caused directly by muscle movement, for example crows-feet type wrinkles when smiling, or forehead furrows when frowning. These types of wrinkles, called "dynamic" wrinkles, appear first in younger people and become permanent with age. If wrinkles appear at rest, ("static" wrinkles) and are associated with sun damage or age-related skin changes it is likely that Botox® will reduce the lines but will not treat them completely. For static wrinkles other treatments such as chemical peels, fillers or laser resurfacing will be necessary.

You should not have Botox® if you are undergoing treatment with aminoglycoside antibiotics such as gentamycin, streptomycin or kanamycin; if you have a neuromuscular condition such as myasthenia gravis, multiple sclerosis or Eaton-Lambert syndrome; or if you are pregnant and/or breast-feeding.

If you are having Botox® injections for the first time, we will carry out small test doses on selected areas only. Every patient differs with their dosage requirement and a fuller treatment will be carried out on the second appointment, after assessment of the effect of the initial dose.

The majority of patients will have a satisfactory response. However, some patients will require a larger dose to have an equivalent effect, while a small minority will not respond at all and may need a different type of medication. The effect of Botox® is temporary and the injections can be repeated with good safety margins. The duration of effect is variable, with most patients needing repeat injections at 4 - 6 month intervals.

 

  • The use of relaxing agents should be limited to selected areas only.
  • The best areas for injection are around the outer rim of the eyes and the ?11? lines between the eyebrows.
  • Excessive dosage can lead to unwanted muscle paralysis and obvious asymmetry.
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